Bystander signaling in C. elegans: proton microbeam studies
نویسندگان
چکیده
منابع مشابه
Bystander signaling in C. elegans: proton microbeam studies
Biological model: In this project, we investigated the control of radiation-induced genotoxic damage expression in somatic cells of the nematode Caenorhabditis elegans. We measured genotoxic damage in the C. elegans intestine by irradiating young larvae with 20 intestinal cells. Fourteen of these cells undergo exactly one nuclear division without cytoplasmic division leading to 14 binucleate ce...
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The understanding of complex radiation responses in biological systems, such as non-targeted effects as represented by the bystander response, can be enhanced by the use of genetically amenable model organisms. Almost all bystander studies to date have been carried out by using conventional single-cell in vitro systems, which are useful tools to characterize basic cellular and molecular respons...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2014
ISSN: 0449-3060,1349-9157
DOI: 10.1093/jrr/rrt178